An in vitro investigation into the efficacies of chlorhexidine gluconate, povidone iodine and green tea (Camellia sinensis) to prevent surgical site infection in animals

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    Abstract

    Background: Surgical site infections are common in veterinary practice; their prevention is based on the preoperative use of topical antimicrobials at the surgical site to reduce resident bacteria to sub-pathogenic levels. Aim Chlorhexidine gluconate (CHG) and povidone iodine (PI) are the most popular options for preoperative skin preparation in veterinary practice, however increasing bacterial resistance to CHG and PI have been reported; therefore investigation into alternative antimicrobials such as Camellia sinensis (green tea: GT) is required. Method The Kirby-Bauer disk diffusion method was used to test the antibacterial activity of four dilutions of CHG, PI and GT on the normal flora of animal skin, represented by S. aureus, S. intermedius, S. uberis and S. pyogenes. Zones of inhibition (ZOI) were measured to assess antimicrobial action. Kruskal-Wallis analyses with Mann-Whitney post-hoc tests determined differences in efficacy between the dilutions of antimicrobials for each bacterium tested. Resul...
    Original languageEnglish
    Pages (from-to)485-492
    Number of pages8
    JournalThe Veterinary Nurse
    Volume7
    Issue number8
    DOIs
    Publication statusPublished - 2 Oct 2016

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