Investigation into the role of five Salmonella enterica serovar Enteritidis genomic islands in colonization of the chicken reproductive tract and other organs following oral challenge

Chris Coward, Leanne Sait, Lisa Williams, Tom J. Humphrey, Tristan Cogan, Duncan J. Maskell

Research output: Contribution to journalJournal Articlepeer-review

Abstract

Salmonella enterica serovar Enteritidis is a major cause of human gastrointestinal tract disease, infection being due in large part to the consumption of contaminated eggs. Recent genome sequencing of S. enterica serovars has identified genomic islands, the presence of which differs between serovars. Using defined mutants, we have investigated the contribution that five such loci play in the colonization of the avian reproductive tract, other organs and avian macrophages. All loci appear to play a small role in infection of liver and spleen, but not in colonization of the reproductive tract or macrophages. © 2012 Federation of European Microbiological Societies.
Original languageEnglish
Pages (from-to)73-78
Number of pages6
JournalFEMS Microbiology Letters
Volume336
Issue number1
DOIs
Publication statusPublished - Nov 2012
Externally publishedYes

Keywords

  • Chicken
  • Colonization
  • Salmonella Enteritidis

Fingerprint Dive into the research topics of 'Investigation into the role of five Salmonella enterica serovar Enteritidis genomic islands in colonization of the chicken reproductive tract and other organs following oral challenge'. Together they form a unique fingerprint.

Cite this