Should an increase in cerebral neurochemicals following head kicks in full contact karate influence return to play?

M. R. Graham, J. Pates, B. Davies, S. M. Cooper, K. Bhattacharya, P. J. Evans, J. S. Baker

Research output: Contribution to journalJournal Article

8 Citations (Scopus)

Abstract

Background: Cerebral neurochemicals are markers of traumatic brain injury (TBI).\nObjectives: The aim of the study was to determine whether kicks to the head (KTH) in full contact karate significantly increased serum concentrations of protein S-100B, and neurone specific enolase (NSE). Kicks to the body (KTB) were also quantified to asses muscle tissue injury. Muscle damage was assessed by analysis of serum total creatine kinase (CK).\nMethods: Twenty-four full contact karate practitioners were observed and filmed during actual competition and divided into two main groups post event: (1) Kicks to the head and body group (KTH): n = 12; mean ± SD; age, 30.4 ± 6.7 years; height, 1.74 ± 0.1 m; weight, 79.1 ± 2.1 kg; and (2): Kicks to the body group (KTB): n = 12; mean ± SD; age, 28.2 ± 6.5 years; height, 1.75 ± 0.1 m; weight, 79.2 ± 1.7 kg. The KTH group received direct kicks to the head, while group KTB received kicks and punches to the body. Blood samples were taken before and immediately post-combat for analysis of serum S-100B, NSE, CK and cardiac troponin.\nResults: Significant increases in serum concentrations of S-100B (0.12 ± 0.17 vs. 0.37 ± 0.26, µg.L−1) and NSE (11.8 ± 4.1 vs. 20.2 ± 9.1 ng.mL−1) were encountered after combat in the KTH group and CK (123 ± 53 vs. 184 ± 103 U.L−1) in the KTB group (all P
Original languageEnglish
Pages (from-to)539-546
Number of pages8
JournalInternational Journal of Immunopathology and Pharmacology
Volume28
Issue number4
DOIs
Publication statusPublished - 1 Dec 2015
Externally publishedYes

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Martial Arts
Phosphopyruvate Hydratase
Creatine Kinase
Head
Serum
Weights and Measures
Muscles
Troponin
Equidae
Protein S
Blood Proteins
Return to Sport
Wounds and Injuries

Keywords

  • NSE
  • S100-B
  • TBI
  • concussion
  • sport

Cite this

Graham, M. R. ; Pates, J. ; Davies, B. ; Cooper, S. M. ; Bhattacharya, K. ; Evans, P. J. ; Baker, J. S. / Should an increase in cerebral neurochemicals following head kicks in full contact karate influence return to play?. In: International Journal of Immunopathology and Pharmacology. 2015 ; Vol. 28, No. 4. pp. 539-546.
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title = "Should an increase in cerebral neurochemicals following head kicks in full contact karate influence return to play?",
abstract = "Background: Cerebral neurochemicals are markers of traumatic brain injury (TBI).\nObjectives: The aim of the study was to determine whether kicks to the head (KTH) in full contact karate significantly increased serum concentrations of protein S-100B, and neurone specific enolase (NSE). Kicks to the body (KTB) were also quantified to asses muscle tissue injury. Muscle damage was assessed by analysis of serum total creatine kinase (CK).\nMethods: Twenty-four full contact karate practitioners were observed and filmed during actual competition and divided into two main groups post event: (1) Kicks to the head and body group (KTH): n = 12; mean ± SD; age, 30.4 ± 6.7 years; height, 1.74 ± 0.1 m; weight, 79.1 ± 2.1 kg; and (2): Kicks to the body group (KTB): n = 12; mean ± SD; age, 28.2 ± 6.5 years; height, 1.75 ± 0.1 m; weight, 79.2 ± 1.7 kg. The KTH group received direct kicks to the head, while group KTB received kicks and punches to the body. Blood samples were taken before and immediately post-combat for analysis of serum S-100B, NSE, CK and cardiac troponin.\nResults: Significant increases in serum concentrations of S-100B (0.12 ± 0.17 vs. 0.37 ± 0.26, µg.L−1) and NSE (11.8 ± 4.1 vs. 20.2 ± 9.1 ng.mL−1) were encountered after combat in the KTH group and CK (123 ± 53 vs. 184 ± 103 U.L−1) in the KTB group (all P",
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Should an increase in cerebral neurochemicals following head kicks in full contact karate influence return to play? / Graham, M. R.; Pates, J.; Davies, B.; Cooper, S. M.; Bhattacharya, K.; Evans, P. J.; Baker, J. S.

In: International Journal of Immunopathology and Pharmacology, Vol. 28, No. 4, 01.12.2015, p. 539-546.

Research output: Contribution to journalJournal Article

TY - JOUR

T1 - Should an increase in cerebral neurochemicals following head kicks in full contact karate influence return to play?

AU - Graham, M. R.

AU - Pates, J.

AU - Davies, B.

AU - Cooper, S. M.

AU - Bhattacharya, K.

AU - Evans, P. J.

AU - Baker, J. S.

PY - 2015/12/1

Y1 - 2015/12/1

N2 - Background: Cerebral neurochemicals are markers of traumatic brain injury (TBI).\nObjectives: The aim of the study was to determine whether kicks to the head (KTH) in full contact karate significantly increased serum concentrations of protein S-100B, and neurone specific enolase (NSE). Kicks to the body (KTB) were also quantified to asses muscle tissue injury. Muscle damage was assessed by analysis of serum total creatine kinase (CK).\nMethods: Twenty-four full contact karate practitioners were observed and filmed during actual competition and divided into two main groups post event: (1) Kicks to the head and body group (KTH): n = 12; mean ± SD; age, 30.4 ± 6.7 years; height, 1.74 ± 0.1 m; weight, 79.1 ± 2.1 kg; and (2): Kicks to the body group (KTB): n = 12; mean ± SD; age, 28.2 ± 6.5 years; height, 1.75 ± 0.1 m; weight, 79.2 ± 1.7 kg. The KTH group received direct kicks to the head, while group KTB received kicks and punches to the body. Blood samples were taken before and immediately post-combat for analysis of serum S-100B, NSE, CK and cardiac troponin.\nResults: Significant increases in serum concentrations of S-100B (0.12 ± 0.17 vs. 0.37 ± 0.26, µg.L−1) and NSE (11.8 ± 4.1 vs. 20.2 ± 9.1 ng.mL−1) were encountered after combat in the KTH group and CK (123 ± 53 vs. 184 ± 103 U.L−1) in the KTB group (all P

AB - Background: Cerebral neurochemicals are markers of traumatic brain injury (TBI).\nObjectives: The aim of the study was to determine whether kicks to the head (KTH) in full contact karate significantly increased serum concentrations of protein S-100B, and neurone specific enolase (NSE). Kicks to the body (KTB) were also quantified to asses muscle tissue injury. Muscle damage was assessed by analysis of serum total creatine kinase (CK).\nMethods: Twenty-four full contact karate practitioners were observed and filmed during actual competition and divided into two main groups post event: (1) Kicks to the head and body group (KTH): n = 12; mean ± SD; age, 30.4 ± 6.7 years; height, 1.74 ± 0.1 m; weight, 79.1 ± 2.1 kg; and (2): Kicks to the body group (KTB): n = 12; mean ± SD; age, 28.2 ± 6.5 years; height, 1.75 ± 0.1 m; weight, 79.2 ± 1.7 kg. The KTH group received direct kicks to the head, while group KTB received kicks and punches to the body. Blood samples were taken before and immediately post-combat for analysis of serum S-100B, NSE, CK and cardiac troponin.\nResults: Significant increases in serum concentrations of S-100B (0.12 ± 0.17 vs. 0.37 ± 0.26, µg.L−1) and NSE (11.8 ± 4.1 vs. 20.2 ± 9.1 ng.mL−1) were encountered after combat in the KTH group and CK (123 ± 53 vs. 184 ± 103 U.L−1) in the KTB group (all P

KW - NSE

KW - S100-B

KW - TBI

KW - concussion

KW - sport

U2 - 10.1177/0394632015577045

DO - 10.1177/0394632015577045

M3 - Journal Article

C2 - 25816397

VL - 28

SP - 539

EP - 546

JO - International Journal of Immunopathology and Pharmacology

JF - International Journal of Immunopathology and Pharmacology

SN - 0394-6320

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