Transgenerational effects modulate density-dependent prophylactic resistance to viral infection in a lepidopteran pest

Kenneth Wilson, Robert I. Graham

Research output: Contribution to journalJournal Article

7 Citations (Scopus)

Abstract

There is an increasing appreciation of the importance of transgenerational effects on offspring fitness, including in relation to immune function and disease resistance. Here, we assess the impact of parental rearing density on offspring resistance to viral challenge in an insect species expressing density-dependent prophylaxis (DDP); i.e. the adaptive increase in resistance or tolerance to pathogen infection in response to crowding. We quantified survival rates in larvae of the cotton leafworm (Spodoptera littoralis) from either gregarious- or solitary-reared parents following challenge with the baculovirus S. littoralis nucleopolyhedrovirus. Larvae from both the parental and offspring generations exhibited DDP, with gregarious-reared larvae having higher survival rates post-challenge than solitary-reared larvae. Within each of these categories, however, survival following infection was lower in those larvae from gregarious-reared parents than those from solitary-reared, consistent with a transgenerational cost of DDP immune upregulation. This observation demonstrates that crowding influences lepidopteran disease resistance over multiple generations, with potential implications for the dynamics of host–pathogen interactions.
Original languageEnglish
JournalBiology Letters
Volume11
Issue number3
DOIs
Publication statusPublished - 1 Mar 2015
Externally publishedYes

Fingerprint

Virus Diseases
Larva
Lepidoptera
pests
larvae
disease control
Crowding
Disease Resistance
infection
Spodoptera littoralis nucleopolyhedrovirus
disease resistance
Survival Rate
survival rate
Nucleopolyhedrovirus
Spodoptera
Spodoptera littoralis
Baculoviridae
Immune System Diseases
Infection
stocking rate

Keywords

  • Density-dependent prophylaxis
  • Immunepriming
  • Insect immunity
  • Nucleopolyhedrovirus
  • Spodoptera littoralis
  • Transgenerational

Cite this

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abstract = "There is an increasing appreciation of the importance of transgenerational effects on offspring fitness, including in relation to immune function and disease resistance. Here, we assess the impact of parental rearing density on offspring resistance to viral challenge in an insect species expressing density-dependent prophylaxis (DDP); i.e. the adaptive increase in resistance or tolerance to pathogen infection in response to crowding. We quantified survival rates in larvae of the cotton leafworm (Spodoptera littoralis) from either gregarious- or solitary-reared parents following challenge with the baculovirus S. littoralis nucleopolyhedrovirus. Larvae from both the parental and offspring generations exhibited DDP, with gregarious-reared larvae having higher survival rates post-challenge than solitary-reared larvae. Within each of these categories, however, survival following infection was lower in those larvae from gregarious-reared parents than those from solitary-reared, consistent with a transgenerational cost of DDP immune upregulation. This observation demonstrates that crowding influences lepidopteran disease resistance over multiple generations, with potential implications for the dynamics of host–pathogen interactions.",
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Transgenerational effects modulate density-dependent prophylactic resistance to viral infection in a lepidopteran pest. / Wilson, Kenneth; Graham, Robert I.

In: Biology Letters, Vol. 11, No. 3, 01.03.2015.

Research output: Contribution to journalJournal Article

TY - JOUR

T1 - Transgenerational effects modulate density-dependent prophylactic resistance to viral infection in a lepidopteran pest

AU - Wilson, Kenneth

AU - Graham, Robert I.

PY - 2015/3/1

Y1 - 2015/3/1

N2 - There is an increasing appreciation of the importance of transgenerational effects on offspring fitness, including in relation to immune function and disease resistance. Here, we assess the impact of parental rearing density on offspring resistance to viral challenge in an insect species expressing density-dependent prophylaxis (DDP); i.e. the adaptive increase in resistance or tolerance to pathogen infection in response to crowding. We quantified survival rates in larvae of the cotton leafworm (Spodoptera littoralis) from either gregarious- or solitary-reared parents following challenge with the baculovirus S. littoralis nucleopolyhedrovirus. Larvae from both the parental and offspring generations exhibited DDP, with gregarious-reared larvae having higher survival rates post-challenge than solitary-reared larvae. Within each of these categories, however, survival following infection was lower in those larvae from gregarious-reared parents than those from solitary-reared, consistent with a transgenerational cost of DDP immune upregulation. This observation demonstrates that crowding influences lepidopteran disease resistance over multiple generations, with potential implications for the dynamics of host–pathogen interactions.

AB - There is an increasing appreciation of the importance of transgenerational effects on offspring fitness, including in relation to immune function and disease resistance. Here, we assess the impact of parental rearing density on offspring resistance to viral challenge in an insect species expressing density-dependent prophylaxis (DDP); i.e. the adaptive increase in resistance or tolerance to pathogen infection in response to crowding. We quantified survival rates in larvae of the cotton leafworm (Spodoptera littoralis) from either gregarious- or solitary-reared parents following challenge with the baculovirus S. littoralis nucleopolyhedrovirus. Larvae from both the parental and offspring generations exhibited DDP, with gregarious-reared larvae having higher survival rates post-challenge than solitary-reared larvae. Within each of these categories, however, survival following infection was lower in those larvae from gregarious-reared parents than those from solitary-reared, consistent with a transgenerational cost of DDP immune upregulation. This observation demonstrates that crowding influences lepidopteran disease resistance over multiple generations, with potential implications for the dynamics of host–pathogen interactions.

KW - Density-dependent prophylaxis

KW - Immunepriming

KW - Insect immunity

KW - Nucleopolyhedrovirus

KW - Spodoptera littoralis

KW - Transgenerational

U2 - 10.1098/rsbl.2015.0012

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